FUT8-IN-1 (Compound 37) is an inhibitor for alpha-1,6-fucosyltransferase (FUT8) with an KD of 49 nM and an IC50 of ca. 50 µM. FUT8-IN-1 generates a highly active naphthoquinone imine intermediate in the presence of FUT8, and inhibits the enzymatic activity of FUT8[1].
Molecular Weight:
380.91
CAS Number:
[3073704-71-6]
Formula:
C23H25ClN2O
Target:
Glucosylceramide Synthase (GCS)
Application Notes:
MCE Product type: Reference compound
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