PKM2-IN-8 (Compound 9b) is a pyruvate kinase M2 (PKM2) inhibitor (IC50 = 0.31 µM). PKM2-IN-8 has potent antiproliferative activity against U87MG glioma cells. PKM2-IN-8 can induce early apoptosis and reduce lactate levels. PKM2-IN-8 can be used for the research of glioblastoma[1].
Molecular Weight:
355.35
Formula:
C19H13N7O
Target:
Apoptosis,Pyruvate Kinase
Application Notes:
MCE Product type: Reference compound
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