Antioxidant agent-20 (Compound 3d) has potent anti-inflammatory and antioxidant activity. Antioxidant agent-20 reduces reactive oxygen species (ROS) and apoptosis in a dose-dependent manner. Antioxidant agent-20 exhibits photoprotective effect against UVB-irradiated human skin keratinocytes (HaCaT) (IC50=5.13 µM) via activation of Nrf2/HO-1 signaling and inhibition of NF-kappaB pathway[1].
Molecular Weight:
304.38
Formula:
C18H24O4
Target:
Apoptosis,Keap1-Nrf2,NF-kappaB,Reactive Oxygen Species (ROS)
Application Notes:
MCE Product type: Reference compound
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