Antitumor agent-192 (Compound 2f) is a beta-carboline antitumor agent. Antitumor agent-192 induces autophagy in HCT116 cells via the ATG5/ATG7 pathway. Antitumor agent-192 has an IC50 of less than 5 µM for human tumor cell lines and significantly inhibits tumor development and reduces tumor weight in a mouse colorectal cancer model transplanted with allografts[1].
Molecular Weight:
570.85
Formula:
C36H54N6
Target:
Atg7,Autophagy
Application Notes:
MCE Product type: Reference compound
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