SMase-IN-1 (Compound 4) is a bacterial sphingomyelinase enzyme (SMase) inhibitor (IC50 value for B. cereus SMase is 6.43 µM). SMase-IN-1 also inhibits eqBuChE (59.50% inhibition rate at 50 µM concentration). SMase-IN-1 forms a complex with Cu2+ in biometal interactions. SMase-IN-1 reduces B. cereus-induced hemolysis on sheep erythrocytes[1].
Molecular Weight:
212.66
CAS Number:
[33017-85-5]
Formula:
C8H5ClN2OS
Target:
Bacterial,Cholinesterase (ChE),Phospholipase
Application Notes:
MCE Product type: Reference compound
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