DDO-02267 is a selective and lysine-targeting covalent inhibitor of ALKBH5, with an IC50 value of 0.49 µM. DDO-02267 increases N6-methyladenosine (m6A) levels and targets the ALKBH5-AXL signaling axis. DDO-02267 can serve as a probe for investigating the biological function of mRNA demethylase[1].
Molecular Weight:
400.36
CAS Number:
[2919768-58-2]
Formula:
C18H12N2O7S
Target:
Anaplastic lymphoma kinase (ALK),Fat Mass and Obesity-associated Protein (FTO)
Application Notes:
MCE Product type: Reference compound
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