PROTAC XPO1 degrader-1 (Compound 2c) is an XPO1 degrader. PROTAC XPO1 degrader-1 exhibits anti-proliferative effects, can induce cell apoptosis, inhibit NF-kappaB activity, and cause cell cycle arrest in the G1 phase. PROTAC XPO1 degrader-1 can be used in research on hematological malignancies (Pink: Target Protein Ligand (HY-170672), Black: Linker (HY-W010525), Blue: E3 Ligase Ligand (HY-170671), E3 Ligase Ligand-Linker Conjugate (HY-170673))[1].
Molecular Weight:
734.12
Purity:
99.92
CAS Number:
[3105680-00-7]
Formula:
C33H35ClF3N7O7
Target:
Apoptosis,CRM1,NF-kappaB,PROTACs
Application Notes:
MCE Product type: Reference compound
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