JAK-IN-39 (compound 11) is a JAK inhibitor that suppresses JAK1, JAK2, JAK3 with IC50 values of 0.05, 1.18, and 0.03 nM, respectively. JAK-IN-39 can inhibit the viability of TF-1 cells and also suppress the production of lymphocyte TNFalpha and INFgamma in vitro[1].
Molecular Weight:
498.54
CAS Number:
[2250013-34-2]
Formula:
C25H26N10O2
Target:
JAK,TNF Receptor
Application Notes:
MCE Product type: Reference compound
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