AH078 (compound 37) is a PROTAC degrader that selectively targets CK1delta and CK1epsilon, and has low targeting for CK1alpha. AH078 consists of PROTAC linker (black part) Monomethyl octanoate (HY-W001958), target protein ligand (red part) (HY-170860) CK1delta/CK1epsilon liagnd-1 and E3 ligase ligand (blue part) E3 ligase Ligand 58 (HY-170861). Among them, E3 ligase ligand + linker can form a conjugate E3 Ligase Ligand-linker Conjugate 163 (HY-170862)[1].
Molecular Weight:
963.15
Formula:
C51H60F2N10O5S
Target:
Casein Kinase
Application Notes:
MCE Product type: Reference compound
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