CAIX/CAXII-IN-4 (Compound 7h) is the inhibitor for carbonic anhydrase (CA) that binds CA IX, CA XII and CA II with Ki of 1.324 µM, 0.435 µM and 3.035 µM. CAIX/CAXII-IN-4 exhibits board-spectrum antitumor efficacy, inhibits the proliferation of CNS cancer U251 with GI50 of 0.361 µM[1].
Molecular Weight:
447.51
Formula:
C23H21N5O3S
Target:
Carbonic Anhydrase
Application Notes:
MCE Product type: Reference compound
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