Pellotine is an alkaloid that can be isolated from Lophophora. Pellotine is the inverse agonist for 5-HT7 receptor with an EC50 of 291 nM. Pellotine exhibits good affinity to 5-HT1DR and 5-HT6R with Ki of 117 nM and 170 nM. Pellotine reduces intracellular cAMP levels, thereby reducing neuronal excitability and neurotransmitter release[1].
Molecular Weight:
237.29
CAS Number:
[19622-05-0]
Formula:
C13H19NO3
Target:
5-HT Receptor
Application Notes:
MCE Product type: Reference compound1
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