A2AR modulator-1, CAS [[3007566-23-3]] Preis auf Anfrage

Product Overview

• Article Name: A2AR modulator-1, CAS [[3007566-23-3]] Preis auf Anfrage
• Biozol Catalog Number: MCE-HY-170948
• Supplier Catalog Number: HY-170948
• Alternative Catalog Number: MCE-HY-170948-1UNIT
• Manufacturer: MedchemExpress
• Category: Biochemikalien

Product Description

A2AR modulator-1 (Compound 45) is a selective negative allosteric adenosine A2a receptor (A2aR) modulator with an IC50 value of 9 nM. A2AR modulator-1 reduces the affinity of endogenous adenosine for the receptor and inhibits cAMP signaling pathway activation. A2AR modulator-1 potently restores pCREB phosphorylation in CD4+ T cells, reversing immunosuppression in the tumor microenvironment, and shows potential to suppress tumor growth and metastasis in triple-negative breast cancer models[1].

Product Properties

• Molecular Weight: 380.45
• CAS Number: [3007566-23-3]
• Formula: C23H20N6
• Target: Adenosine Receptor

Application Notes

• Application Notes: MCE Product type: Reference compound1