AR antagonist 10, CAS [[3068489-78-8]] Preis auf Anfrage

Product Overview

• Article Name: AR antagonist 10, CAS [[3068489-78-8]] Preis auf Anfrage
• Biozol Catalog Number: MCE-HY-170951
• Supplier Catalog Number: HY-170951
• Alternative Catalog Number: MCE-HY-170951-1UNIT
• Manufacturer: MedchemExpress
• Category: Biochemikalien

Product Description

AR antagonist 10 (Compound Y5) is potent and orally active androgen receptor (AR) antagonist with an IC50 of 0.04 µM. AR antagonist 10 demonstrates dual mechanisms of action, antagonizes AR by disrupting AR dimerization, and induces AR degradation via the ubiquitin-proteasome pathway. AR antagonist 10 exhibits excellent activity against variant drug-resistant AR mutants. AR antagonist 10 effectively suppresses the tumor growth of the LNCaP xenograft. AR antagonist 10 is potential to be used for drug-resistant prostate cancer[1].

Product Properties

• Molecular Weight: 404.87
• CAS Number: [3068489-78-8]
• Formula: C18H17ClN4O3S
• Target: Androgen Receptor

Application Notes

• Application Notes: MCE Product type: Reference compound1