BRD4 degrader-5 (Compound 23) is a hydrophobic tag (HyTag)-based protein degrader for BRD4 (DC50 = 24.7 µM) through ER stress and autophagy-lysosome pathway. BRD4 degrader-5 inhibits the proliferation of cancer cell 4T1 with an IC50 of 20.6 µM[1].
Molecular Weight:
660.27
Formula:
C35H42ClN7O2S
Target:
AUTACs,Autophagy,Epigenetic Reader Domain
Application Notes:
MCE Product type: Reference compound
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