I2-IRs ligand-1 (Compound 12d) is an orally active and BBB-penetrable compound. I2-IRs ligand-1 has a high affinity for imidazoline I2 receptors (I2-IRs) (pKi: 9.98). I2-IRs ligand-1 can improve cognitive impairment in senescent mice and exhibits analgesic, anti-inflammatory, and neuroprotective activities. I2-IRs ligand-1 can be used for the research of Alzheimers disease and related pain disorders[1].
Molecular Weight:
452.84
Formula:
C21H23ClFN2O4P
Target:
Imidazoline Receptor
Application Notes:
MCE Product type: Reference compound1
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