IRF1-IN-1 (Compound I-2) is an IRF1 inhibitor. IRF1-IN-1 decreases the recruitment of IRF1 to the promoter of CASP1. IRF1-IN-1 inhibits cell death signaling pathway (i.e., cleavage of Caspase 1, GSDMD, IL-1 and PARP1). IRF1-IN-1 has a protective effect on ionizing radiation-induced inflammatory skin injury[1].
Molecular Weight:
440.52
Purity:
99.72
CAS Number:
[701225-07-2]
Formula:
C22H24N4O4S
Target:
Caspase,IFNAR,Interleukin Related,PARP,Pyroptosis
Application Notes:
MCE Product type: Reference compound1
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