PQA-18 is a unique PAK2 inhibitor (IC50: 10 nM). PQA-18 has immunosuppressing effects. PQA-18 suppresses IL2, IL4, IL6, and TNFalpha. PQA-18 inhibits the population of a subset of regulatory T cells and the immunoglobulin (Ig) production against T cell-dependent antigens as well as alleviates dermatitis in mice[1].
Molecular Weight:
409.52
Purity:
99.62
CAS Number:
[1604678-82-1]
Formula:
C25H31NO4
Target:
Interleukin Related,PAK,TNF Receptor
Application Notes:
MCE Product type: Reference compound
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