GAPDH-IN-1 (Compound F8) is a GAPDH inhibitor (IC50 of 39.31 µM for GAPDH enzymatic activity). GAPDH-IN-1 forms a covalent adduct with an aspartic acid in the active site to displace NAD+, a cofactor of the enzyme, with concomitant enhancement of the cysteine-reactive probe reaction with the catalytic cysteine[1].
Molecular Weight:
366.37
Purity:
98.1
CAS Number:
[252212-58-1]
Formula:
C20H18N2O5
Target:
Endogenous Metabolite
Application Notes:
MCE Product type: Reference compound
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