Amyloid-beta-IN-2 (Compound EX.112) is a selective gamma-secretase inhibitor. Amyloid-beta-IN-2 inhibits Abeta42 secretion in H4 cells with an EC50 value of 226 nM. Amyloid-beta-IN-2 is promising for research of Alzheimers disease (AD) and other diseases related to Abeta deposition[1].
Molecular Weight:
397.42
Purity:
99.47
CAS Number:
[1603833-55-1]
Formula:
C22H21F2N3O2
Target:
Amyloid-beta,gamma-secretase
Application Notes:
MCE Product type: Reference compound
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