ATR-IN-32 is an orally active ATR inhibitor. ATR-IN-32 potently inhibits the proliferation of MIA PaCa-2 cells. ATR-IN-32 exerts significant tumor growth inhibition in mice bearing LOVO and HT-29 xenografts. ATR-IN-32 can be used for the study of cancers mediated by ATR protein kinase, such as colorectal cancer, pancreatic cancer[1].
Molecular Weight:
404.46
Purity:
96.69
CAS Number:
[2902715-97-1]
Formula:
C22H24N6O2
Target:
ATM/ATR
Application Notes:
MCE Product type: Reference compound
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