SK2187 is a selective AURKA PROTAC degrader with a DC50 of about 10 nM. SK2187 exhibits growth inhibition against NGP cells with an IC50 of 101.5 nM. SK2187 can be used for the study of MYCN-amplified neuroblastoma (Pink: AURKA ligand: MK-5108 (HY-13252), Blue: E3 ligand (HY-103597), Black: Linker: Amino-PEG3-alcohol (HY-W015088))[1].
Molecular Weight:
950.43
Purity:
95.81
CAS Number:
[3038446-91-9]
Formula:
C45H49ClFN7O11S
Target:
Aurora Kinase,PROTACs
Application Notes:
MCE Product type: Reference compound
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