DN-108, a thiazolidinedione derivative, is an orally active peroxisome proliferator-activated receptor gamma (PPARgamma) agonist with antidiabetic effects. DN-108 improves hyperglycemia, hypertriglyceridemia and hyperinsulinemia in diabetic mouse models. DN-108 enhances tissue glucose uptake (e.g., increasing 2-deoxyglucose uptake in L6 muscle cells) and inhibits fatty acid synthase activity. DN-108 is promising for research of type 2 diabetes[1].
Molecular Weight:
366.43
CAS Number:
[195604-21-8]
Formula:
C20H18N2O3S
Target:
PPAR
Application Notes:
MCE Product type: Reference compound
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