AZD1134 is an orally active, brain-penetrant and highly selective 5-HT1B receptor antagonist with IC50 values of 2.9 nM (human) and 0.108 nM (guinea pig), respectively. AZD1134 increases synaptic serotonin levels in guinea pigs. AZD1134 is promising for research of psychiatric disorders, such as depression and anxiety[1].
Molecular Weight:
521.58
CAS Number:
[442548-99-4]
Formula:
C28H32FN5O4
Target:
5-HT Receptor
Application Notes:
MCE Product type: Reference compound
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