SIAIS001 is a potent and orally active PROTAC ALK degrader with a DC50 of 3.9 nM. SIAIS001 induces G1/S phase cell cycle arrest and inhibits proliferation of SR cells (IC50 = 0.9 nM). SIAIS001 can be used for non-small cell lung cancer (NSCLC) and anaplastic large-cell lymphomas (ALCLs) research[1].
Molecular Weight:
789.96
CAS Number:
[2570251-63-5]
Formula:
C48H51N7O4
Target:
Anaplastic lymphoma kinase (ALK),PROTACs
Application Notes:
MCE Product type: Reference compound
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