DPC 684 is a potent and selective HIV-1 protease inhibitor (IC90 = 5.7-40 nM, Ki = 0.021 nM). DPC 684 competitively inhibits HIV-1 protease and blocks viral polyprotein cleavage. DPC 684 has low protein binding and broad-spectrum inhibition against a variety of wild-type and mutant HIV-1 proteases. DPC 684 has low protein binding and broad-spectrum inhibition (IC90 = 1.9-6.3 nM). DPC 684 has research significance for HIV[1].
Molecular Weight:
669.85
CAS Number:
[284661-73-0]
Formula:
C35H48FN5O5S
Target:
HIV,HIV Protease
Application Notes:
MCE Product type: Reference compound
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