SB-583355 (Compound 56) is a potent G2A antagonist. SB-583355 can be prepared by a Suzuki reaction between 4-methoxyphenyl boronic acid and 3-bromo-4-hydroxybenzoic acid following the conditions followed by an amide coupling reaction. SB-583355 blocks the activation of G2A mediated either by 9-HOPE or T-10148 in human G2A expressing CHO-K1 cells. SB-583355 can be studied in research for inflammation, myeloid leukemia, and neuropathic pain[1].
Molecular Weight:
472.58
CAS Number:
[3040121-49-8]
Formula:
C29H32N2O4
Target:
G2A (GPR132)
Application Notes:
MCE Product type: Reference compound
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