BI-8128 is a potent EGFR inhibitor, with IC50 values of 12, 6.7, 22, 10, and 3 nM against wild-type, T790M, C797S, T790M/C797S, and L858R/T790M/C797S mutant EGFR, respectively. BI-8128 significantly inhibits the proliferation of Ba/F3 and PC-9 drug-resistant mutant cells. BI-8128 is applicable for the research of non-small cell lung cancer[1].
Molecular Weight:
610.71
CAS Number:
[2769714-36-3]
Formula:
C32H38N10O3
Target:
EGFR
Application Notes:
MCE Product type: Reference compound
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