CZY43 is a HER3 degrader. CZY43 can effectively induce HER3 degradation in a dose- and time-dependent manner in breast cancer SKBR3 cells. CZY43 potently inhibits HER3-dependent signaling and cancer cell growth and outperforms Bosutinib (HY-10158)[1].
Molecular Weight:
746.81
Formula:
C42H53Cl2N5O3
Target:
EGFR
Application Notes:
MCE Product type: Reference compound
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