p38-alpha MAPK-IN-8 (Compound 13) is a lipophilic cationic derivative. p38-alpha MAPK-IN-8 is cytotoxic to various tumor cells, and can induce cell cycle arrest, apoptosis, increase reactive oxygen species (ROS) production, and induce mitochondrial membrane potential depolarization. The antitumor activity of p38-alpha MAPK-IN-8 may be related to p38alpha MAPK pathway, which can be used in the study of cancer[1].
Molecular Weight:
825.89
Formula:
C49H62BrO4P
Target:
Apoptosis,p38 MAPK,Reactive Oxygen Species (ROS)
Application Notes:
MCE Product type: Reference compound
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