BGC4 is a biphenyl-based gold(III) complex. BGC4 inhibits human recombinant thioredoxin reductase (TrxR) with an IC50 of 10.7 µM, exhibits cytotoxicity (IC50 for MDA-MB-231 is 5.4 µM), and induces apoptosis. BGC4 exhibits antitumor efficacy in mouse models[1].
Molecular Weight:
725.02
Formula:
C30H33AuClF3N3
Target:
Apoptosis,TrxR
Application Notes:
MCE Product type: Reference compound
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