CCR6 antagonist 2 (Compound 20c) is the antagonist for CCR6 with a Ki of 1.1 nM. CCR6 antagonist 2 inhibits CCL20-induced calcium ion influx (IC50 = 4.9 nM), inhibits the chemotactic migration of CCR6+ T cells (IC50 = 190 nM)[1].
Molecular Weight:
372.42
Formula:
C19H24N4O4
Target:
CCR
Application Notes:
MCE Product type: Reference compound
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