TS-IN-6 (Compound 10) is a thymidylate synthase (TS) inhibitor with an IC50 value of 0.54 µM, demonstrating significant antiproliferative activity. TS-IN-6 induces G1 phase cell cycle arrest and apoptosis (marked by substantial increases in both early and late apoptotic rates) and shows potential for research on cancers such as colon, breast, and liver cancers[1].
Molecular Weight:
540.59
Formula:
C29H22F2N6OS
Target:
Apoptosis,Thymidylate Synthase
Application Notes:
MCE Product type: Reference compound
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