SIRT-IN-7 (Compound 7ba) is a SIRT inhibitor. SIRT-IN-7 can inhibit the expression of SIRT1, SIRT2, and SIRT3, and increase the acetylation and activation of p53. SIRT-IN-7 can inhibit the proliferation, and induce apoptosis and autophagy of breast cancer cells. SIRT-IN-7 has anti-tumor activity[1].
Molecular Weight:
495.82
CAS Number:
[1620634-65-2]
Formula:
C24H16BrClN2OS
Target:
Apoptosis,Autophagy,MDM-2/p53,Sirtuin
Application Notes:
MCE Product type: Reference compound
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