AB-343 is a selective covalent inhibitor of SARS-CoV-2 Mpro, with an IC50 of 8 nM and a Ki of 2.8 nM. AB-343 can effectively inhibit the main proteases of SARS-CoV-2 and many other coronaviruses, and is also active against some resistant variants. AB-343 can be used in the research of treating coronavirus infection-related diseases[1][2].
Molecular Weight:
575.57
Formula:
C26H34F5N5O4
Target:
SARS-CoV,Virus Protease
Application Notes:
MCE Product type: Reference compound
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