Mal-amide-PEG8-Val-Cit-PAB-PNP is a cleavable ADC linker featuring a maleimide, a PEG spacer, a Val-Cit dipeptide, a PAB. and a PNP carbonate. Maleimide is a thiol-specific covalent linker which is used to label cysteine residues in proteins while the PNP group acts as a highly activated leaving group. Val-Cit linkers are cleaved by cytoplasmic peptidases.
Molecular Weight:
1119.17
CAS Number:
[1964490-09-2]
Formula:
C51H74N8O20
Target:
ADC Linker
Application Notes:
MCE Product type: ADC Related
* VAT and and shipping costs not included. Errors and price changes excepted