Succinate dehydrogenase-IN-6 (Compound E23) is the inhibitor for succinate dehydrogenase that inhibits SDH in Rhizoctonia solani with an IC50 of 11.76 µM. Succinate dehydrogenase-IN-6 disrupts fungal cell membrane, exhibits board-spectrum antifungal activity that inhibits R. solani, V. dahliae, A. solani and C. gloeosporioides with EC50s of 0.41, 0.27, 1.15, 0.27 µg/mL, respectively. Succinate dehydrogenase-IN-6 exhibits no significant toxicity in rice and zebrafish (LC50 > 12.5 µg/mL)[1].
Molecular Weight:
316.26
Formula:
C15H10F2N4O2
Target:
Fungal,Succinate Dehydrogenase
Application Notes:
MCE Product type: Reference compound
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