PLK1-IN-12 is a highly selective and orally active PLK1 inhibitor with an IC50 of 20 nM. PLK1-IN-12 shows more selective for PLK1 than PLK2 (IC50: >10000 nM) and PLK3 (IC50: 3953 nM). PLK1-IN-12 exhibits anticancer potency across a broad spectrum of cell lines. PLK1-IN-12 can be used in anti-leukemia research[1].
Molecular Weight:
558.12
Formula:
C28H40ClN7O3
Target:
Polo-like Kinase (PLK)
Application Notes:
MCE Product type: Reference compound
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