TopoII/tubulin-IN-1 (Compound 1B8) is a TopoII/tubulin inhibitor. TopoII/tubulin-IN-1 can inhibit the proliferation and the level of ROS of tumor cells, induce apoptosis and cell cycle arrest of tumor cells, but has no significant cytotoxicity to normal cells. TopoII/tubulin-IN-1 has antitumor activity[1].
Molecular Weight:
423.85
Formula:
C21H18ClN5O3
Target:
Apoptosis,Microtubule/Tubulin,Reactive Oxygen Species (ROS),Topoisomerase
Application Notes:
MCE Product type: Reference compound
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