Blixeprodil (GM-1020) is the orally active antagonist for NMDA receptor with an affinity of Ki=3.25 µM in rat cortical tissue. Blixeprodil inhibits NR1/2A-NMDAR-mediated currents in HEK293 cell with IC50 of 1.192 µM. Blixeprodil exhibits antidepressant in rats models. Blixeprodil can cross blood-brain barrier[1].
Molecular Weight:
221.27
Purity:
95
CAS Number:
[2881017-49-6]
Formula:
C13H16FNO
Target:
iGluR
Application Notes:
MCE Product type: Reference compound
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