JSF-4898 is an orally active inhibitor of the MenG enzyme in Mycobacterium tuberculosis. JSF-4898 has MIC of 0.78 µM against Mycobacterium tuberculosis H37Rv. JSF-4898 can enhance the efficacy of Rifampicin (HY-B0272) in a subacute model of Mycobacterium tuberculosis infection in mice[1].
Molecular Weight:
417.86
Formula:
C21H21ClFN3O3
Target:
Bacterial
Application Notes:
MCE Product type: Reference compound
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