HDAC3-IN-7 (Compound 8ae) is a selective HDAC3 inhibitor with an IC50 value of 311 nM. HDAC3-IN-7 degrades PD-L1 through the lysosome pathway mediated by Cathepsin B, exerting activities such as inhibiting tumor cell proliferation, migration, and invasion. HDAC3-IN-7 is promising for research of cancers[1].
Molecular Weight:
503.66
Formula:
C25H37N5O4S
Target:
HDAC,PD-1/PD-L1
Application Notes:
MCE Product type: Reference compound
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