Orexin 2 Receptor Agonist 3 (Compound 57) is an orally active and brain-penetrant orexin receptor type-2 (OX2) agonist (EC50: 2.5 nM). Orexin 2 Receptor Agonist 3 increases wakefulness in the orexin/ataxin-3 NT1 mouse model and healthy beagle dogs. Orexin 2 Receptor Agonist 3 can be used in the study of narcolepsy[1].
Molecular Weight:
537.56
Formula:
C27H29F2N7O3
Target:
Orexin Receptor (OX Receptor)
Application Notes:
MCE Product type: Reference compound
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