PUC-10 is a 5-HT6 receptor antagonist with a Ki of 14.6 nM and an IC50 of 32 nM. In silico predictions suggest that PUC-10 is orally active and can cross the blood-brain barrier. PUC-10 can induce autophagy in SH-SY5Y cells by inhibiting the mTOR pathway. PUC-10 can be used in the research of neurological disorders[1].
Molecular Weight:
541.66
CAS Number:
[2064126-76-5]
Formula:
C31H31N3O4S
Target:
5-HT Receptor,Autophagy,mTOR
Application Notes:
MCE Product type: Reference compound
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