PRMT5-IN-50, CAS [[3002409-47-1]] Preis auf Anfrage
Biozol Catalog Number:
MCE-HY-172732
Supplier Catalog Number:
HY-172732
Alternative Catalog Number:
MCE-HY-172732-1UNIT
Manufacturer:
MedchemExpress
Category:
Biochemikalien
PRMT5-IN-50 is an orally active and selective inhibitor of PRMT5. PRMT5-IN-50 has good metabolic stability and low clearance rate in human liver microsomes. PRMT5-IN-50 inhibits SDMA/HCT116-MTAPdel and SDMA/HCT116-MTAPwt with IC50s value of 1.0, 536 nM for arginine symmetric methylation, 19, 1620 nM for anti-proliferation, respectively. PRMT5-IN-50 inhibits tumor growth in mice[1].
Molecular Weight:
492.50
CAS Number:
[3002409-47-1]
Formula:
C26H23F3N6O
Target:
Histone Methyltransferase
Application Notes:
MCE Product type: Reference compound
* VAT and and shipping costs not included. Errors and price changes excepted