AX-53802 is a ferroptosis inducer targeting GPX4 with an IC50 of 0.34 µM. AX-53802 forms a covalent bond with GPX4, initiating membrane translocation directly upon binding. AX-53802 and FAK/Src inhibitors promotes cell death. AX-53802 can be used for cancer study[1].
Molecular Weight:
408.42
CAS Number:
[1008482-71-0]
Formula:
C23H21FN2O4
Target:
Ferroptosis,Glutathione Peroxidase
Application Notes:
MCE Product type: Reference compound
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