KMG-1068 (Compound 4a), a molecular glue, is a GSPT1/2 degrader. KMG-1068 effectively induces the CRBN-dependent degradation of GSPT1/2 by binding to the IMiD binding site on CRBN, facilitating the formation of a ternary complex with GSPT1/2. KMG-1068 is promising for research of cancers[1].
Molecular Weight:
426.49
Purity:
99.73
CAS Number:
[3113750-79-8]
Formula:
C21H22N4O4S
Target:
Molecular Glues
Application Notes:
MCE Product type: Reference compound
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