BuChE-IN-20 is a selective butyrylcholinesterase (hBuChE) inhibitor (IC50 = 0.13 µM) with BBB permeability. BuChE-IN-20 is a L-Tryptophan derivative. BuChE-IN-20 possesses neuroprotective properties by inhibiting the production of nitric oxide (NO) and lowering the levels of ROS. BuChE-IN-20 is proficient in inhibiting the self-aggregation of amyloid-beta (Abeta) peptides. BuChE-IN-20 can be used in research for Alzheimers disease[1].
Molecular Weight:
484.56
Formula:
C29H29FN4O2
Target:
Amyloid-beta,Cholinesterase (ChE),Interleukin Related,NOD-like Receptor (NLR),Reactive Oxygen Species (ROS)
Application Notes:
MCE Product type: Reference compound
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