Aromatase-IN-5 (Compound 10) is a potent inhibitor of aromatase with an IC50 value of 0.06 µM. Aromatase-IN-5 effectively blocks estrogen production. Aromatase-IN-5 inhibits the proliferation of breast cancer cell lines like MCF-7, arrests the cell cycle at the G1 phase, and induces apoptosis. Aromatase-IN-5 is promising for research of breast cancer[1].
Molecular Weight:
509.99
Formula:
C22H16ClN7O2S2
Target:
Apoptosis,Cytochrome P450
Application Notes:
MCE Product type: Reference compound
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