NLRP3-IN-78, CAS [[477546-27-3]] Preis auf Anfrage
Biozol Catalog Number:
MCE-HY-172788
Supplier Catalog Number:
HY-172788
Alternative Catalog Number:
MCE-HY-172788-1UNIT
Manufacturer:
MedchemExpress
Category:
Biochemikalien
NLRP3-IN-78 (compound 21) is a NLRP3 inhibitor with the inhibition rate of 46.72% in GSDMD-induced pyroptosis at 5 µM. NLRP3-IN-78 binds to the NLRP3 protein and inhibits GSDMD-NT oligomerization. NLRP3-IN-78 also inhibits GSDMD cleavage, and upstream NF-kappaB signaling, demonstrating its anti-inflammatory activity[1].
Molecular Weight:
390.22
CAS Number:
[477546-27-3]
Formula:
C12H5Cl2N3O4S2
Target:
NF-kappaB,Pyroptosis
Application Notes:
MCE Product type: Reference compound
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