KL4-219A is a selective covalent oncogenic transcription factor MYC degrader. KL4-219A potently and durably degrades MYC in cancer cells. KL4-219A binds covalently to MYC at C203, leading to the destabilization of MYC and subsequent proteasome-dependent degradation. KL4-219A is promising for research of cancers driven by MYC overexpression[1].
Molecular Weight:
370.47
Purity:
99.85
Formula:
C20H22N2O3S
Target:
c-Myc
Application Notes:
MCE Product type: Reference compound
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